B5056
Sigma
Bioinformatics Basics: Applications in Biological Science and Medicine
| ISBN-10: | 0-8493-2375-4 |
| ISBN-13: | 978-0-8493-2375-1 |
Description
| General description | Scientists use an extensive databank to access structural information on proteins and nucleic acids and a specialized form of software to analyze the hybridization pattern of DNA chips. The success of biotechnology and pharmaceutical industries has been a result of technical advancements in genomics, proteomics, and bioinformatics. This book describes the organization of public domain databases with a tutorial for the services described. It concentrates on three major database clusters and relevant software tools that are maintained in the US, Europe, and Japan. |
Properties
| publication info | H.H. Rashidi and L.K. Buehler, ed., CRC Press, 2000, 200 pp., hard cover |
Table Of Contents
| Table of Contents | INTRODUCTION Biology and Bioinformatics The Nature of Publicly Funded Research Genomics and Proteomics Metabolic Databases Public and Proprietary Bioinformatics Computers in Biology and Medicine Computer Algorithms Super Computers Limitations of Computational Tools - Paradoxical Promise of the Internet The Need For Computational Tools New Approaches to Scientific Research With Computers Biological Macromolecules Proteins Protein Structure Protein Folding Protein Function DNA and RNA Structure Nucleic Acid Structure and Function Genetic Code DATABASES AND SEARCH TOOLS Computational Tools and Databases National Center for Biotechnology Information (NCBI) European Bioinformatics Institute (EBI) Genome Net - Japanese Bioinformatics Servers Database Mining Tools Sequence Similarity Search Tools: BLAST Pattern Recognition Tools and Databases GENOME ANALYSIS DNA Cloning and PCR DNA Cloning Transcriptional Profiling Positional Cloning Polymer Chain Reaction PCR Technologies Under Development Monitoring Sequencing Progress Computational Tools for DNA Sequence Analysis Database Sequence Submission Data Retrieval Sequence Alignment Biological Function of Sequences - Annotation Identifying ORFs and URFs Redundancy in Sequence Data Better Search Engines for Better Computers? Genome Analysis The Genome Organization Mapping the Genome Human Genome Mapping Progress Functional Genomics Unidentified Reading Frames Cluster of Orthologous Groups PROTEOME ANALYSIS Proteomics 2D Page at Expasy Yeast Proteome Database Metabolic Reconstruction KEGG: Kyoto Encyclopedia of Genes and Genomes The Functional Reconstruction Model E.coli Metabolic Database - EcoCyc Where should we be in the future? COMPUTER REVOLUTION IN NEUROBIOLOGY Human Brain Project The Influence of Computers in Science Computers in Neurobiology and the Mapping of the Human Brain From Molecules to Neurodegenerative Diseases Computer Simulations and Visualization of Molecular Structures Computer Simulations and Visualization of Molecular Structures Predictive Biology Protein Structure Prediction Structure Prediction Software |
